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SAMSN1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| IHC-P, FC, WB, E |
|---|---|
| Primary Accession | Q9NSI8 |
| Other Accession | NP_071419.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 41708 Da |
| Antigen Region | 255-283 aa |
| Gene ID | 64092 |
|---|---|
| Other Names | SAM domain-containing protein SAMSN-1, Hematopoietic adaptor containing SH3 and SAM domains 1, Nash1, SAM domain, SH3 domain and nuclear localization signals protein 1, SH3-SAM adaptor protein, SAMSN1, HACS1 |
| Target/Specificity | This SAMSN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-283 amino acids from the Central region of human SAMSN1. |
| Dilution | IHC-P~~1:50~100 FC~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SAMSN1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SAMSN1 |
|---|---|
| Synonyms | HACS1 |
| Function | Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation (By similarity). |
| Cellular Location | Nucleus. Cytoplasm. Cell projection, ruffle. Note=Shuttles between cytoplasm and nucleus. Colocalizes with the actin cytoskeleton and actin-rich membrane ruffles (By similarity). |
| Tissue Location | Detected in peripheral blood B-cells (at protein level). Detected in spleen, liver and peripheral blood |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 150.00
$ 385.00
Cat# AP5877c
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