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SHOC2 Polyclonal Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SHOC2 Polyclonal Antibody AP58801
    Sample:
    Lane 1: Cerebrum (Mouse) Lysate at 40 ug
    Lane 2: Testis (Mouse) Lysate at 40 ug
    Lane 3: Esophagus (Mouse) Lysate at 40 ug
    Lane 4: Large intestine (Mouse) Lysate at 40 ug
    Lane 5: NIH/3T3 (Mouse) Cell Lysate at 30 ug
    Lane 6: Cerebrum (Rat) Lysate at 40 ug
    Lane 7: Testis (Rat) Lysate at 40 ug
    Lane 8: Esophagus (Rat) Lysate at 40 ug
    Lane 9: Large intestine (Rat) Lysate at 40 ug
    Lane 10: A549 (Human) Cell Lysate at 30 ug
    Lane 11: U937 (Human) Cell Lysate at 30 ug
    Lane 12: HL60 (Human) Cell Lysate at 30 ug
    Primary:
    Anti- SHOC2 (bs-7934R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 62 kD
    Observed band size: 60 kD
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IHC-F, IF
Primary Accession Q9UQ13
Reactivity Rat, Dog, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 64888 Da
Additional Information
Gene ID 8036
Other Names Leucine-rich repeat protein SHOC-2, Protein soc-2 homolog, Protein sur-8 homolog, SHOC2, KIAA0862
Dilution WB=1:500-2000,Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,
Format0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce
StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃.
Protein Information
Name SHOC2
Synonyms KIAA0862
Function Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.
Cellular Location Cytoplasm. Nucleus. Note=Translocates from cytoplasm to nucleus upon growth factor stimulation.
Research Areas
Citations (0)
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$ 350.00
Cat# AP58801
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Availability: 2 weeks
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