C2orf43 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IHC-F, IF, IEM |
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Primary Accession | Q9H6V9 |
Reactivity | Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 37319 Da |
Gene ID | 60526 |
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Other Names | Lipid droplet-associated hydrolase {ECO:0000312|HGNC:HGNC:26145}, 3.1.1.-, Lipid droplet-associated serine hydrolase, hLDAH, LDAH {ECO:0000303|PubMed:24357060, ECO:0000312|HGNC:HGNC:26145} |
Dilution | WB=1:500-2000,Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,IEM=1:20-200,IGS=1:20-200,GICA=1:20-200, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | LDAH {ECO:0000303|PubMed:24357060, ECO:0000312|HGNC:HGNC:26145} |
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Function | Probable serine lipid hydrolase associated with lipid droplets. Appears to lack cholesterol esterase activity. Appears to lack triglyceride lipase activity. Highly expressed in macrophage-rich areas in atherosclerotic lesions, suggesting that it could promote cholesterol ester turnover in macrophages. |
Cellular Location | Lipid droplet. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8BVA5}. Note=Localizes to the endoplasmic reticulum in absence of lipid droplets and translocates to lipid droplets upon lipid storage induction {ECO:0000250|UniProtKB:Q8BVA5} |
Tissue Location | Present in macrophage-rich areas in atherosclerotic lesionsv(at protein level). |
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