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Anti-PSMC6 Antibody
Rabbit polyclonal antibody to PSMC6
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Application 
| WB, IP |
|---|---|
| Primary Accession | P62333 |
| Other Accession | P62334 |
| Reactivity | Human, Mouse, Rat, Zebrafish, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 44173 Da |
| Gene ID | 5706 |
|---|---|
| Other Names | SUG2; 26S protease regulatory subunit 10B; 26S proteasome AAA-ATPase subunit RPT4; Proteasome 26S subunit ATPase 6; Proteasome subunit p42 |
| Target/Specificity | Recognizes endogenous levels of PSMC6 protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IP (1/10 - 1/100) IP~~N/A |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | PSMC6 |
|---|---|
| Synonyms | SUG2 |
| Function | Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides. |
| Cellular Location | Cytoplasm. Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PSMC6. The exact sequence is proprietary.
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