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Anti-TWEAK Antibody
Rabbit polyclonal antibody to TWEAK
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- BACKGROUND
Application 
| WB, IP |
|---|---|
| Primary Accession | O43508 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 27216 Da |
| Gene ID | 407977;8742 |
|---|---|
| Other Names | APO3L; DR3LG; Tumor necrosis factor ligand superfamily member 12; APO3 ligand; TNF-related weak inducer of apoptosis; TWEAK |
| Target/Specificity | Recognizes endogenous levels of TWEAK protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IP (1/10 - 1/100) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | TNFSF12 |
|---|---|
| Synonyms | APO3L, DR3LG |
| Function | Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion. |
| Cellular Location | Cell membrane; Single-pass type II membrane protein [Isoform TWE-PRIL]: Cell membrane; Single-pass membrane protein |
| Tissue Location | Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Also detected in fetal kidney, liver, lung and brain |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TWEAK. The exact sequence is proprietary.
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