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Anti-ELOVL6 Antibody

Rabbit polyclonal antibody to ELOVL6

     
  • WB - Anti-ELOVL6 Antibody AP59871
    Western blot analysis of ELOVL6 expression in Hela (A), A549 (B), mouse liver (C), rat liver (D) whole cell lysates.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IP
Primary Accession Q9H5J4
Other Accession Q920L5
Reactivity Human, Mouse, Rat, Chicken
Host Rabbit
Clonality Polyclonal
Calculated MW 31376 Da
Additional Information
Gene ID 79071
Other Names FACE; LCE; Elongation of very long chain fatty acids protein 6; 3-keto acyl-CoA synthase ELOVL6; ELOVL fatty acid elongase 6; ELOVL FA elongase 6; Fatty acid elongase 2; hELO2; Fatty acyl-CoA elongase; Long-chain fatty-acyl elongase; Very-long-chain 3-oxoacyl-CoA synthase 6
Target/Specificity Recognizes endogenous levels of ELOVL6 protein.
Dilution WB~~WB (1/500 - 1/1000), IP (1/10 - 1/100)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name ELOVL6 {ECO:0000255|HAMAP-Rule:MF_03206}
Synonyms FACE, LCE
Function Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Cellular Location Endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_03206, ECO:0000269|PubMed:20937905}; Multi- pass membrane protein {ECO:0000255|HAMAP-Rule:MF_03206}
Tissue Location Ubiquitous..
Research Areas
Citations (0)
citation

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Background

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ELOVL6. The exact sequence is proprietary.

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$ 350.00
$ 175.00
Cat# AP59871
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