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Anti-AP2 gamma Antibody
Rabbit polyclonal antibody to AP2 gamma
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- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q92754 |
| Other Accession | Q61312 |
| Reactivity | Human, Mouse, Rat, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 49177 Da |
| Gene ID | 7022 |
|---|---|
| Other Names | Transcription factor AP-2 gamma; AP2-gamma; Activating enhancer-binding protein 2 gamma; Transcription factor ERF-1 |
| Target/Specificity | Recognizes endogenous levels of AP2 gamma protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/100 - 1/200) IHC~~1:100~500 |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | TFAP2C |
|---|---|
| Function | Sequence-specific DNA-binding transcription factor that interacts with cellular enhancer elements to regulate transcription of selected genes, and which plays a key role in early embryonic development (PubMed:11694877, PubMed:24413532). AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions (PubMed:11694877, PubMed:24413532). TFAP2C plays a key role in early embryonic development by regulating both inner cell mass (ICM) and trophectoderm differentiation (By similarity). At the 8-cell stage, during morula development, controls expression of cell-polarity genes (By similarity). Upon trophoblast commitment, binds to late trophectoderm genes in blastocysts together with CDX2, and later to extra-embryonic ectoderm genes together with SOX2 (By similarity). Binds to both closed and open chromatin with other transcription factors (By similarity). Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer (PubMed:24413532). |
| Cellular Location | Nucleus. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human AP2 gamma. The exact sequence is proprietary.
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$ 385.00
$ 195.00
Cat# AP60060
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