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Anti-ANGPTL7 Antibody

Rabbit polyclonal antibody to ANGPTL7

     
  • WB - Anti-ANGPTL7 Antibody AP60082
    Western blot analysis of ANGPTL7 expression in HEK293T (A), rat liver (B) whole cell lysates.
    detail
  • IH - Anti-ANGPTL7 Antibody AP60082
    Immunohistochemical analysis of ANGPTL7 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IP, IHC
Primary Accession O43827
Other Accession Q8R1Q3
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 40018 Da
Additional Information
Gene ID 10218
Other Names CDT6; Angiopoietin-related protein 7; Angiopoietin-like factor; Angiopoietin-like protein 7; Cornea-derived transcript 6 protein
Target/Specificity Recognizes endogenous levels of ANGPTL7 protein.
Dilution WB~~WB (1/500 - 1/1000), IH (1/100 - 1/200), IP (1/10 - 1/100)
IH~~WB (1/500 - 1/1000), IH (1/100 - 1/200), IP (1/10 - 1/100)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name ANGPTL7
Synonyms CDT6
Function Has a role in the formation and organization of the extracellular matrix. In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure (PubMed:21199193). Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency (PubMed:25622036).
Cellular Location Secreted.
Tissue Location Highly expressed in the cornea (at protein level) (PubMed:11682471). Expression is restricted to the stromal layer (PubMed:11682471). Also detected at the junction between the corneal stromal layer and the conjuctiva. Not detected in the sclera (PubMed:11682471).
Research Areas
Citations (0)
citation

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Background

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ANGPTL7. The exact sequence is proprietary.

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$ 350.00
$ 175.00
Cat# AP60082
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