Anti-DBI Antibody
Rabbit polyclonal antibody to DBI
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | P07108 |
Other Accession | P31786 |
Reactivity | Human, Mouse, Rat, Pig |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 10044 Da |
Gene ID | 1622 |
---|---|
Other Names | Acyl-CoA-binding protein; ACBP; Diazepam-binding inhibitor; DBI; Endozepine; EP |
Target/Specificity | Recognizes endogenous levels of DBI protein. |
Dilution | WB~~WB (1/500 - 1/1000) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | DBI |
---|---|
Function | Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. |
Cellular Location | Endoplasmic reticulum. Golgi apparatus Note=Golgi localization is dependent on ligand binding (PubMed:17953517). |
Tissue Location | Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human DBI. The exact sequence is proprietary.
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