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Anti-IGFBP3 Antibody
Rabbit polyclonal antibody to IGFBP3
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | P17936 |
| Other Accession | P47878 |
| Reactivity | Human, Mouse, Rat, Monkey, Pig, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 31674 Da |
| Gene ID | 3486 |
|---|---|
| Other Names | IBP3; Insulin-like growth factor-binding protein 3; IBP-3; IGF-binding protein 3; IGFBP-3 |
| Target/Specificity | Recognizes endogenous levels of IGFBP3 protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/50 - 1/200) IH~~WB (1/500 - 1/1000), IH (1/50 - 1/200) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | IGFBP3 |
|---|---|
| Synonyms | IBP3 |
| Function | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. Inhibits the positive effect of humanin on insulin sensitivity (PubMed:19623253). Promotes testicular germ cell apoptosis (PubMed:19952275). |
| Cellular Location | Secreted. |
| Tissue Location | Expressed by most tissues. Present in plasma. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IGFBP3. The exact sequence is proprietary.
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