Anti-Delta Opioid Receptor (pS363) Antibody
Rabbit polyclonal antibody to Delta Opioid Receptor (pS363)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IF/IC, IHC |
---|---|
Primary Accession | P41143 |
Other Accession | P32300 |
Reactivity | Human, Mouse, Rat, Pig |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 40369 Da |
Gene ID | 4985 |
---|---|
Other Names | OPRD; Delta-type opioid receptor; D-OR-1; DOR-1 |
Target/Specificity | Recognizes endogenous levels of Delta Opioid Receptor (pS363) protein. |
Dilution | WB~~WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500) IH~~WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500) IF~~WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | OPRD1 |
---|---|
Synonyms | OPRD |
Function | G-protein coupled receptor that functions as a receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine. |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Detected in oocytes (at protein level). Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Delta Opioid Receptor (pS363). The exact sequence is proprietary.
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