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Anti-TEAD2 Antibody
Rabbit polyclonal antibody to TEAD2
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF/IC, IHC |
|---|---|
| Primary Accession | Q15562 |
| Other Accession | P48301 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 49243 Da |
| Gene ID | 8463 |
|---|---|
| Other Names | TEF4; Transcriptional enhancer factor TEF-4; TEA domain family member 2; TEAD-2 |
| Target/Specificity | Recognizes endogenous levels of TEAD2 protein. |
| Dilution | WB~~WB (1/500 - 1/2000), IH (1/50 - 1/200), IF/IC (1/50 - 1/100), ChIP (1/100 - 1/500) IF~~WB (1/500 - 1/2000), IH (1/50 - 1/200), IF/IC (1/50 - 1/100), ChIP (1/100 - 1/500) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | TEAD2 |
|---|---|
| Synonyms | TEF4 |
| Function | Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif. |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TEAD2. The exact sequence is proprietary.
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