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Anti-GDI2 Antibody

Rabbit polyclonal antibody to GDI2

     
  • WB - Anti-GDI2 Antibody AP60863
    Western blot analysis of GDI2 expression in A549 (A), Hela (B), LOVO (C), BV2 (D), PC12 (E) whole cell lysates.
    detail
  • IH - Anti-GDI2 Antibody AP60863
    Immunohistochemical analysis of GDI2 staining in mouse brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession P50395
Other Accession Q61598
Reactivity Human, Mouse, Rat, Pig, Bovine, Drosophila
Host Rabbit
Clonality Polyclonal
Calculated MW 50663 Da
Additional Information
Gene ID 2665
Other Names RABGDIB; Rab GDP dissociation inhibitor beta; Rab GDI beta; Guanosine diphosphate dissociation inhibitor 2; GDI-2
Target/Specificity Recognizes endogenous levels of GDI2 protein.
Dilution WB~~WB (1/500 - 1/2000), IH (1/50 - 1/200)
IH~~WB (1/500 - 1/2000), IH (1/50 - 1/200)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name GDI2
Synonyms RABGDIB
Function GDP-dissociation inhibitor preventing the GDP to GTP exchange of most Rab proteins. By keeping these small GTPases in their inactive GDP-bound form regulates intracellular membrane trafficking (PubMed:25860027). Negatively regulates protein transport to the cilium and ciliogenesis through the inhibition of RAB8A (PubMed:25860027).
Cellular Location Cytoplasm. Membrane; Peripheral membrane protein
Tissue Location Ubiquitous..
Research Areas
Citations (0)
citation

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Background

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GDI2. The exact sequence is proprietary.

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$ 350.00
$ 175.00
Cat# AP60863
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