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Anti-CLK4 Antibody
Rabbit polyclonal antibody to CLK4
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- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q9HAZ1 |
| Other Accession | O35493 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 57492 Da |
| Gene ID | 57396 |
|---|---|
| Other Names | Dual specificity protein kinase CLK4; CDC-like kinase 4 |
| Target/Specificity | Recognizes endogenous levels of CLK4 protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/50 - 1/100) IH~~WB (1/500 - 1/1000), IH (1/50 - 1/100) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | CLK4 |
|---|---|
| Function | Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. |
| Cellular Location | Nucleus. |
| Tissue Location | Expressed in liver, kidney, heart, muscle, brain and endothelial cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CLK4. The exact sequence is proprietary.
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