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Anti-GAB2 (pY643) Antibody
Rabbit polyclonal antibody to GAB2 (pY643)
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Application 
| WB, IHC |
|---|---|
| Primary Accession | Q9UQC2 |
| Other Accession | Q9Z1S8 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 74458 Da |
| Gene ID | 9846 |
|---|---|
| Other Names | KIAA0571; GRB2-associated-binding protein 2; GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp100 |
| Target/Specificity | Recognizes endogenous levels of GAB2 (pY643) protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/50 - 1/200) IH~~WB (1/500 - 1/1000), IH (1/50 - 1/200) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | GAB2 |
|---|---|
| Synonyms | KIAA0571 |
| Function | Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. |
| Cellular Location | Cytoplasm. Cell membrane. Membrane raft {ECO:0000250|UniProtKB:Q9Z1S8} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GAB2 (pY643). The exact sequence is proprietary.
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