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Anti-NEK9 Antibody
Rabbit polyclonal antibody to NEK9
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF/IC |
|---|---|
| Primary Accession | Q8TD19 |
| Other Accession | Q8K1R7 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 107168 Da |
| Gene ID | 91754 |
|---|---|
| Other Names | KIAA1995; NEK8; NERCC; Serine/threonine-protein kinase Nek9; Nercc1 kinase; Never in mitosis A-related kinase 9; NimA-related protein kinase 9; NimA-related kinase 8; Nek8 |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human NEK9. The exact sequence is proprietary. |
| Dilution | WB~~WB (1/500 - 1/1000), IF/IC (1/100 - 1/500) IF/IC~~N/A |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | NEK9 {ECO:0000303|PubMed:12840024, ECO:0000312|HGNC:HGNC:18591} |
|---|---|
| Function | Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation (PubMed:12101123, PubMed:12840024, PubMed:14660563, PubMed:19941817). Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2 (PubMed:11864968). Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues (PubMed:11864968). Important for G1/S transition and S phase progression (PubMed:12840024, PubMed:14660563, PubMed:19941817). Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively (PubMed:12840024, PubMed:14660563, PubMed:19941817, PubMed:26522158). |
| Cellular Location | Cytoplasm. Nucleus |
| Tissue Location | Most abundant in heart, liver, kidney and testis. Also expressed in smooth muscle cells and fibroblasts |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human NEK9. The exact sequence is proprietary.
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$ 195.00
$ 385.00
Cat# AP61293
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