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Anti-RFX2 Antibody
Rabbit polyclonal antibody to RFX2
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | P48378 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 79987 Da |
| Gene ID | 5990 |
|---|---|
| Other Names | DNA-binding protein RFX2; Regulatory factor X 2 |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RFX2. The exact sequence is proprietary. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/50 - 1/200) IHC~~1:100~500 |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | RFX2 |
|---|---|
| Function | Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function (By similarity). Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters (PubMed:10330134). Probably activates transcription of the testis-specific histone gene H1-6 (By similarity). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:B2GV50, ECO:0000255|PROSITE-ProRule:PRU00858}. Cytoplasm {ECO:0000250|UniProtKB:B2GV50}. Note=Mainly expressed in the nucleus and at lower level in cytoplasm. {ECO:0000250|UniProtKB:B2GV50} |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RFX2. The exact sequence is proprietary.
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