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Anti-MYPT1 Antibody
Rabbit polyclonal antibody to MYPT1
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- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | O14974 |
| Other Accession | Q9DBR7 |
| Reactivity | Human, Mouse, Rat, Zebrafish, Chicken |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 115281 Da |
| Gene ID | 4659 |
|---|---|
| Other Names | MBS; MYPT1; Protein phosphatase 1 regulatory subunit 12A; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit |
| Target/Specificity | Recognizes endogenous levels of MYPT1 protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/100 - 1/200) IH~~WB (1/500 - 1/1000), IH (1/100 - 1/200) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | PPP1R12A (HGNC:7618) |
|---|---|
| Function | Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity. |
| Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton, stress fiber. Note=Also along actomyosin filaments |
| Tissue Location | Expressed in striated muscles, specifically in type 2a fibers (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MYPT1. The exact sequence is proprietary.
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