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CFHL1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CFHL1 Antibody (C-term) AP6615b
    Western blot analysis of CFHL1 antibody (C-term) (Cat. #AP6615b) in K562 cell line lysates (35ug/lane). CFHL1 (arrow) was detected using the purified Pab.
    detail
  • IHC-P - CFHL1 Antibody (C-term) AP6615b
    Formalin-fixed and paraffin-embedded human hepatocarcinoma with CFHL1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
    detail
  • FC - CFHL1 Antibody (C-term) AP6615b
    Flow cytometric analysis of K562 cells using CFHL1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, FC, E
Primary Accession Q03591
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 37651 Da
Antigen Region 270-297 aa
Additional Information
Gene ID 3078
Other Names Complement factor H-related protein 1, FHR-1, H factor-like protein 1, H-factor-like 1, H36, CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2
Target/Specificity This CFHL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-297 amino acids from the C-terminal region of human CFHL1.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCFHL1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CFHR1
Synonyms CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1,
Function Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism.
Cellular Location Secreted.
Tissue Location Expressed by the liver and secreted in plasma.
Research Areas
Citations (0)
citation

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Background

CFHL1 might be involved in complement regulation. The protein can associate with lipoproteins and may play a role in lipid metabolism.

References

Grosskinsky,S., PLoS ONE 4 (3), E4858 (2009)
Siegel,C., J. Biol. Chem. 283 (50), 34855-34863 (2008)

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$ 365.00
$ 140.00
Cat# AP6615b
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