CCDC102B Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | Q68D86 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 60448 Da |
Gene ID | 79839 |
---|---|
Other Names | CCDC102B; C18orf14; Coiled-coil domain-containing protein 102B |
Dilution | WB~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
Storage Conditions | -20℃ |
Name | CCDC102B |
---|---|
Synonyms | C18orf14 |
Function | During interphase, forms fibers at the proximal ends of centrioles to maintain centrosome cohesion (PubMed:30404835). During mitosis, dissociates from the centrosome following phosphorylation to allow centrosome separation (PubMed:30404835). Contributes to CROCC/rootletin filament formation (PubMed:30404835). |
Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note=Concentrated at the proximal ends of centrioles where it forms fibers (PubMed:30404835). Centrosomal localization becomes weak when cells enter prophase and is significantly decreased in metaphase (PubMed:30404835). |
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