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C102B Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IHC-P, E |
|---|---|
| Primary Accession | Q68D86 |
| Other Accession | NP_079057.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 60448 Da |
| Antigen Region | 472-500 aa |
| Gene ID | 79839 |
|---|---|
| Other Names | Coiled-coil domain-containing protein 102B, CCDC102B, C18orf14 |
| Target/Specificity | This C102B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 472-500 amino acids from the C-terminal region of human C102B. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | C102B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CCDC102B |
|---|---|
| Synonyms | C18orf14 |
| Function | During interphase, forms fibers at the proximal ends of centrioles to maintain centrosome cohesion (PubMed:30404835). During mitosis, dissociates from the centrosome following phosphorylation to allow centrosome separation (PubMed:30404835). Contributes to CROCC/rootletin filament formation (PubMed:30404835). |
| Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note=Concentrated at the proximal ends of centrioles where it forms fibers (PubMed:30404835). Centrosomal localization becomes weak when cells enter prophase and is significantly decreased in metaphase (PubMed:30404835). |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Miller, Y.E., et al. Genomics 8(1):149-154(1990)
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$ 365.00
$ 140.00
Cat# AP5377b
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