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KV9.2 Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9ULS6 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 54237 Da |
| Gene ID | 3788 |
|---|---|
| Other Names | KCNS2; KIAA1144; Potassium voltage-gated channel subfamily S member 2; Delayed-rectifier K(+) channel alpha subunit 2; Voltage-gated potassium channel subunit Kv9.2 |
| Dilution | WB~~Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
| Storage Conditions | -20℃ |
| Name | KCNS2 (HGNC:6301) |
|---|---|
| Synonyms | KIAA1144 |
| Function | Potassium channel regulatory subunit that modulate the delayed rectifier voltage-gated potassium channel activity of KCNB1 and KCNB2 by altering their kinetics, expression levels, and shifting the half-inactivation potential to more polarized values. While it does not form functional channels on its own, it can form functional heterotetrameric channels with KCNB1 and KCNB2. Each regulatory subunit has unique regulatory properties that can lead to extensive inhibition, significant changes in kinetics, and/or substantial shifts in the voltage dependencies of the inactivation process. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:O35174}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O35174}. Note=May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 or KCNB2 {ECO:0000250|UniProtKB:O35174} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage- gated potassium channel activation and deactivation rates of KCNB1 and KCNB2.
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