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RCL1 Polyclonal Antibody

     
  • WB - RCL1 Polyclonal Antibody AP72216
    detail
  •  - RCL1 Polyclonal Antibody AP72216
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9Y2P8
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 40843 Da
Additional Information
Gene ID 10171
Other Names RCL1; RNAC; RPC2; RPCL1; RTC2; HSPC338; RNA 3'-terminal phosphate cyclase-like protein
Dilution WB~~Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃
Protein Information
Name RCL1 (HGNC:17687)
Synonyms RNAC, RPC2, RPCL1, RTC2
Function Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre- rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre- ribosomal RNA by the RNA exosome (PubMed:34516797). Does not have cyclase activity (By similarity).
Cellular Location Nucleus, nucleolus.
Citations (0)
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Background

Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity).

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$ 350.00
Cat# AP72216
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Availability: 2 weeks
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