WISP-3 Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | O95389 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 39293 Da |
Gene ID | 8838 |
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Other Names | WNT1-inducible-signaling pathway protein 3 (WISP-3) (CCN family member 6) |
Dilution | WB~~WB 1:500-2000, ELISA 1:10000-20000 |
Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
Storage Conditions | -20℃ |
Name | CCN6 (HGNC:12771) |
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Function | Plays a role in mitochondrial electron transport and mitochondrial respiration (PubMed:27252383). Through its regulation of the mitochondrial function may play a role in normal postnatal skeletal growth and cartilage homeostasis (PubMed:27252383, PubMed:10471507). |
Cellular Location | Secreted. Mitochondrion. Note=Associated with membranes. |
Tissue Location | Predominant expression in adult kidney and testis and fetal kidney. Weaker expression found in placenta, ovary, prostate and small intestine (PubMed:9843955, PubMed:10471507). Also expressed in skeletally-derived cells such as synoviocytes and articular cartilage chondrocytes (PubMed:10471507). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Appears to be required for normal postnatal skeletal growth and cartilage homeostasis.
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