SAE1 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, ICC |
|---|---|
| Primary Accession | Q9UBE0 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 38450 Da |
| Gene ID | 10055 |
|---|---|
| Other Names | SAE1 |
| Dilution | WB~~1/500-1/1000 ICC~~N/A |
| Format | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Name | SAE1 |
|---|---|
| Synonyms | AOS1, SUA1, UBLE1A |
| Function | The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. |
| Cellular Location | Nucleus. |
| Tissue Location | Expression level increases during S phase and drops in G2 phase (at protein level). |

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