UFC1 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IP, ICC |
---|---|
Primary Accession | Q9Y3C8 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 19458 Da |
Gene ID | 51506 |
---|---|
Other Names | UFC1 |
Dilution | WB~~1/500-1/1000 IP~~N/A ICC~~N/A |
Format | Liquid |
Name | UFC1 {ECO:0000303|PubMed:15071506, ECO:0000312|HGNC:HGNC:26941} |
---|---|
Function | E2-like enzyme which specifically catalyzes the second step in ufmylation (PubMed:15071506, PubMed:29868776, PubMed:30626644, PubMed:34588452, PubMed:35394863, PubMed:36121123, PubMed:38383789). Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage (PubMed:15071506, PubMed:29868776, PubMed:34588452, PubMed:38383789). Ufmylation is involved in various processes, such as ribosome recycling, response to DNA damage, interferon response or reticulophagy (also called ER-phagy) (PubMed:27351204, PubMed:32160526, PubMed:35394863, PubMed:37036982, PubMed:38383789). |

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