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Mitofusin 1 Rabbit mAb
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- CITATIONS
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- BACKGROUND
Application 
| WB, IP |
|---|---|
| Primary Accession | Q8R4Z9 |
| Reactivity | Mouse, Rat, Hamster |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 83847 Da |
| Gene ID | 192647 |
|---|---|
| Other Names | Mfn1 |
| Dilution | WB~~1/500-1/1000 IP~~1/20 |
| Format | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Name | Mfn1 |
|---|---|
| Synonyms | Fzo1b |
| Function | Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:12589796, PubMed:14561718). Membrane clustering requires GTPase activity. It may involve a major rearrangement of the coiled coil domains (By similarity). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:14561718). Overexpression induces the formation of mitochondrial networks (in vitro) (PubMed:14561718). Has low GTPase activity (By similarity). |
| Cellular Location | Mitochondrion outer membrane; Multi-pass membrane protein |
| Tissue Location | Ubiquitous. In brain, it is expressed at weaker level than MFN2, while it is expressed at a higher level than MFN2 in heart and testis. Expressed at high level in elongating spermatids of seminiferous tubules. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 385.00
Cat# AP76591
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