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STK38L Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9Y2H1 |
| Other Accession | Q7TSE6 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 54003 Da |
| Antigen Region | 408-437 aa |
| Gene ID | 23012 |
|---|---|
| Other Names | Serine/threonine-protein kinase 38-like, NDR2 protein kinase, Nuclear Dbf2-related kinase 2, STK38L {ECO:0000312|EMBL:AAH286031} |
| Target/Specificity | This STK38L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-437 amino acids from the C-terminal region of human STK38L. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | STK38L Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | STK38L {ECO:0000312|EMBL:AAH28603.1} |
|---|---|
| Function | Involved in the regulation of structural processes in differentiating and mature neuronal cells. |
| Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton. Membrane. Note=Associated with the actin cytoskeleton. Co-localizes with STK24/MST3 in the membrane |
| Tissue Location | Ubiquitously expressed with highest levels observed in the thymus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
STK38L contains 12 protein kinase catalytic subdomains and a potential bipartite nuclear localization signal. Northern blot analysis revealed expression of a 3.9-kb transcript in all tissues tested, with the possible exception of adult brain. Highest expression was in peripheral blood leukocytes. Immunoblot and immunofluorescence microscopy demonstrated predominantly nuclear expression of a 55-kD protein.
References
Devroe, E., et al., J. Biol. Chem. 279(23):24444-24451 (2004).
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