Hsp20 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, IHC-P, FC |
|---|---|
| Primary Accession | O14558 |
| Reactivity | Rat, Human, Mouse |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Immunogen | A synthesized peptide derived from human Hsp20 |
| Purification | Affinity Chromatography |
| Calculated MW | Calculated MW: 17 kDa; Observed MW: 17 kDa |
| Gene ID | 126393 |
|---|---|
| Other Names | HSPB6 |
| Dilution | WB~~1/500-1/1000 IHC-P~~N/A FC~~1:10~50 |
| Format | Liquid in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Name | HSPB6 |
|---|---|
| Function | Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity. |
| Cellular Location | Cytoplasm. Nucleus. Secreted Note=Translocates to nuclear foci during heat shock |

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