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AMPD3 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q01432 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 88812 Da |
| Antigen Region | 325-356 aa |
| Gene ID | 272 |
|---|---|
| Other Names | AMP deaminase 3, AMP deaminase isoform E, Erythrocyte AMP deaminase, AMPD3 |
| Target/Specificity | This AMPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-356 amino acids from the Central region of human AMPD3. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | AMPD3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | AMPD3 (HGNC:470) |
|---|---|
| Function | AMP deaminase plays a critical role in energy metabolism. |
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Provided below are standard protocols that you may find useful for product applications.
Background
AMPD3 is a member of the AMP deaminase gene family. This protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. The protein is the erythrocyte (E) isoforms, whereas other family members isoforms predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency.
References
Mahnke-Zizelman D.K., Eddy R.Biochim. Biophys. Acta 1306:75-92(1996)
Yamada Y., Goto H., Wakamatsu N., Ogasawara N.Hum. Mutat. 17:78-78(2001)
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