NME6 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | O75414 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 21142 Da |
Antigen Region | 80-110 aa |
Gene ID | 10201 |
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Other Names | Nucleoside diphosphate kinase 6, NDK 6, NDP kinase 6, Inhibitor of p53-induced apoptosis-alpha, IPIA-alpha, nm23-H6, NME6 |
Target/Specificity | This NME6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-110 amino acids from the N-terminal region of human NME6. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | NME6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NME6 |
---|---|
Function | Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis. |
Tissue Location | Expressed at a moderately low level in many tissues. Most abundant in kidney, prostate, ovary, intestine, and spleen |
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Provided below are standard protocols that you may find useful for product applications.
Background
NME6 plays a major role in the synthesis of nucleoside triphosphates other than ATP. It is an inhibitor of p53-induced apoptosis. NME6 is expressed at a moderately low level in many tissues, most abundantly in kidney, prostate, ovary, intestine, and spleen.
References
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).
Mehus, J.G., et al., Hum. Genet. 104(6):454-459 (1999).
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