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BIN3 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q9NQY0 |
| Other Accession | Q5PPZ5 |
| Reactivity | Human |
| Predicted | Xenopus |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 29665 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 55909 |
|---|---|
| Other Names | Bridging integrator 3, BIN3 |
| Target/Specificity | This BIN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BIN3. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | BIN3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BIN3 |
|---|---|
| Function | Involved in cytokinesis and septation where it has a role in the localization of F-actin. |
| Cellular Location | Cytoplasm, cytoskeleton. |
| Tissue Location | Ubiquitously expressed except in brain. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
BIN3 is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes.
References
Ren,G., et.al., Microbiol. Mol. Biol. Rev. 70 (1), 37-120 (2006)
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