BIN3 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q9NQY0 |
Other Accession | Q5PPZ5 |
Reactivity | Human |
Predicted | Xenopus |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 29665 Da |
Antigen Region | 1-30 aa |
Gene ID | 55909 |
---|---|
Other Names | Bridging integrator 3, BIN3 |
Target/Specificity | This BIN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BIN3. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | BIN3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | BIN3 |
---|---|
Function | Involved in cytokinesis and septation where it has a role in the localization of F-actin. |
Cellular Location | Cytoplasm, cytoskeleton. |
Tissue Location | Ubiquitously expressed except in brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
BIN3 is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes.
References
Ren,G., et.al., Microbiol. Mol. Biol. Rev. 70 (1), 37-120 (2006)
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