Pax2 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC, FC |
---|---|
Primary Accession | Q02962 |
Reactivity | Human, Mouse |
Clonality | Monoclonal |
Other Names | PAX2; Paired box protein Pax-2 |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 44706 Da |
Dilution | WB 1:500~1:2000 IHC 1:50~1:200 FC 1:50 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Pax2 |
Description | PAX2 mutations can be responsible for renal hypoplasia, either isolated or associated with various ophthalmologic manifestations ranging from retinal coloboma to microphthalmia. Lesions in the PAX6 gene accounts for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | PAX2 |
---|---|
Function | Transcription factor that may have a role in kidney cell differentiation (PubMed:24676634). Has a critical role in the development of the urogenital tract, the eyes, and the CNS. |
Cellular Location | Nucleus. |
Tissue Location | Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system |

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