Phospho-Glycogen synthase 1 (S641) Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC, ICC, IP |
---|---|
Primary Accession | P13807 |
Clonality | Monoclonal |
Other Names | glycogen [starch] synthase, muscle; glycogen synthase, muscle; GYS; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 83786 Da |
Dilution | WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Phospho-Glycogen synthase 1 (S641) |
Description | Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. Allosteric activation by glucose-6-phosphate. Phosphorylation reduces the activity towards UDP-glucose. When in the non-phosphorylated state, glycogen synthase does not require glucose-6-phosphate as an allosteric activator; when phosphorylated it does. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | GYS1 (HGNC:4706) |
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Synonyms | GYS |
Function | Glycogen synthase participates in the glycogen biosynthetic process along with glycogenin and glycogen branching enzyme. Extends the primer composed of a few glucose units formed by glycogenin by adding new glucose units to it. In this context, glycogen synthase transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. |
Tissue Location | Expressed in skeletal muscle and most other cell types where glycogen is present. |

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