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NSD3 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC |
|---|---|
| Primary Accession | Q9BZ95 |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Other Names | Wolf Hirschhorn syndrome candidate 1 like 1; WHSC1L1; NSD3; pp14328; Histone-lysine N-methyltransferase NSD3; Protein whistle; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 161613 Da |
| Dilution | WB 1:1000~1:5000 FC 1:30 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human NSD3 |
| Description | This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. The function of the protein has not been determined. Two alternatively spliced variants have been described. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | NSD3 (HGNC:12767) |
|---|---|
| Synonyms | WHSC1L1 |
| Function | Histone methyltransferase. Preferentially dimethylates 'Lys- 4' and 'Lys-27' of histone H3 forming H3K4me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. |
| Cellular Location | Nucleus. Chromosome. |
| Tissue Location | Highly expressed in brain, heart and skeletal muscle. Expressed at lower level in liver and lung |
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 195.00
$ 385.00
Cat# AP90698
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