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IRF6 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, ICC |
|---|---|
| Primary Accession | O14896 |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Other Names | Interferon regulatory factor 6; IRF 6; LPS;OFC 6; PIT; PPS; PPS1; VWS; VWS1; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 53130 Da |
| Dilution | WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human IRF6 |
| Description | Play an important role in pathogen defense, autoimmunity, lymphocyte development, cell growth, and susceptibility to transformation. Plays a role in regulating mammary epithelial cell proliferation (By similarity). May regulate WDR65 transcription. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | IRF6 |
|---|---|
| Function | Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity). Plays a role in regulating mammary epithelial cell proliferation (By similarity). May regulate WDR65 transcription (By similarity). |
| Cellular Location | Nucleus. Cytoplasm Note=Translocates to nucleus in response to an activating signal |
| Tissue Location | Expressed in normal mammary epithelial cells. Expression is reduced or absent in breast carcinomas |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
$ 175.00
Cat# AP90818
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