HSPB8/HSP22 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC, ICC |
---|---|
Primary Accession | Q9UJY1 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | CMT2L; CRYAC; DHMN2; E2IG1; H11; HMN2; HSPB8; HSP22; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 21604 Da |
Dilution | WB 1:500~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:100 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human HSPB8/HSP22 |
Description | HSPB8 (HSP22) is a member of the small heat shock protein superfamily and the human protein is most closely related to HSP27. Similar to most other small HSPs (sHSPs), HSPB8 is predominantly transcribed in skeletal muscle and heart. In a two hybrid screen, HSPB8 interacted preferentially with a triple aspartate form of HSP27 which mimics HSP27 phosphorylated at Ser15, Ser78, and Ser82, as compared to wild-type HSP27. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | HSPB8 |
---|---|
Synonyms | CRYAC, E2IG1, HSP22 |
Function | Displays temperature-dependent chaperone activity. |
Cellular Location | Cytoplasm. Nucleus Note=Translocates to nuclear foci during heat shock |
Tissue Location | Predominantly expressed in skeletal muscle and heart. |

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