Endothelin B Receptor Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IP |
---|---|
Primary Accession | P24530 |
Clonality | Monoclonal |
Other Names | ABCDS; Ednra; EDNRB; Endothelin B receptor precursor; ETB; ETBR; ETRB; Hirschsprung disease; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 49644 Da |
Dilution | WB 1:500~1:2000 IP 1:50 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Endothelin B Receptor |
Description | Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | EDNRB (HGNC:3180) |
---|---|
Synonyms | ETRB |
Function | Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Cellular Location | Cell membrane; Multi-pass membrane protein. Note=internalized after activation by endothelins. |
Tissue Location | Expressed in placental stem villi vessels, but not in cultured placental villi smooth muscle cells |

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