NEFM Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, IHC, ICC, IP |
|---|---|
| Primary Accession | P07197 |
| Clonality | Monoclonal |
| Other Names | 150kDa medium; NEF3; NEFM; Neurofilament 3; NF160; NFM; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 102472 Da |
| Dilution | WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:20 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human NEFM |
| Description | Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The 16 α and 8 β subunits heterodimerize to produce more than 20 different receptors. Antibodies to this protein are useful to identify neurons and their processes in tissue sections and in tissue culture. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | NEFM |
|---|---|
| Synonyms | NEF3, NFM |
| Function | Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity). |
| Cellular Location | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P08553}. Cell projection, axon {ECO:0000250|UniProtKB:P08553} |

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