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HIST1H1C Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - HIST1H1C Antibody (Center) AP9164c
    All lanes : Anti-HIST1H1C Antibody (Center) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: A375 whole cell lysate Lane 3: 293 whole cell lysate Lane 4: HUVEC whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 21 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P16403
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 21365 Da
Antigen Region 105-131 aa
Additional Information
Gene ID 3006
Other Names Histone H12, Histone H1c, Histone H1d, Histone H1s-1, HIST1H1C, H1F2
Target/Specificity This HIST1H1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-131 amino acids from the Central region of human HIST1H1C.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHIST1H1C Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name H1-2 (HGNC:4716)
Function Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
Cellular Location Nucleus. Chromosome. Note=Mainly localizes in euchromatin. Distribution goes in parallel with DNA concentration
Citations (0)
citation

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Background

Histones H1 are necessary for the condensation of nucleosome chains into higher order structures.

References

Mayya V., et.al., Sci. Signal. 2:RA46-RA46(2009).

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$ 182.50
$ 70.00
Cat# AP9164c
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