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SEC23 Antibody

Rabbit mAb

     
  •  - SEC23 Antibody AP91749
    Western blot analysis of SEC23 expression in HeLa cell lysate.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, FC
Primary Accession Q15436
Clonality Monoclonal
Other Names CLSD; sec23a;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 86161 Da
Additional Information
Dilution WB 1:1000~1:5000 FC 1:50
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human SEC23
Description Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name SEC23A (HGNC:10701)
Function Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane (By similarity).
Cellular Location Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol. Note=Enriched at endoplasmic reticulum exit sites, also known as transitional endoplasmic reticulum (tER)
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)
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$ 350.00
$ 175.00
Cat# AP91749
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