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C4 binding protein Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, ICC, IP |
|---|---|
| Primary Accession | P20851 |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Other Names | C4BP; C4BPB; PRP; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 28357 Da |
| Dilution | WB 1:500~1:1000 IHC 1:100~1:500 ICC/IF 1:50~1:200 IP 1:60 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human C4 binding protein |
| Description | Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | C4BPB |
|---|---|
| Function | Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S. |
| Cellular Location | Secreted. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 195.00
$ 385.00
Cat# AP91817
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