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Plexin A1 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q9UIW2 |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Other Names | NOV; NOVP; Plexin-A1; Plexin1; PlexinA1; PLXN1; Plxna1; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 211067 Da |
| Dilution | WB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:50 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human Plexin A1 |
| Description | Plays a role in axon guidance, invasive growth and cell migration. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | PLXNA1 (HGNC:9099) |
|---|---|
| Synonyms | NOV, PLXN1 |
| Function | Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. Acts as coreceptor of TREM2 for SEMA6D in dendritic cells and is involved in the generation of immune responses and skeletal homeostasis. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:P70206}; Single-pass type I membrane protein |
| Tissue Location | Detected in fetal brain, lung, liver and kidney. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 385.00
$ 195.00
Cat# AP91862
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