S39A3 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-P, WB, E |
---|---|
Primary Accession | Q9BRY0 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 33601 Da |
Antigen Region | 106-134 aa |
Gene ID | 29985 |
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Other Names | Zinc transporter ZIP3, Solute carrier family 39 member 3, Zrt- and Irt-like protein 3, ZIP-3, SLC39A3, ZIP3 |
Target/Specificity | This S39A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the Central region of human S39A3. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | S39A3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SLC39A3 (HGNC:17128) |
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Synonyms | ZIP3 |
Function | Transporter for the divalent cation Zn(2+). Mediates the influx of Zn(2+) into cells from extracellular space. Controls Zn(2+) accumulation into dentate gyrus granule cells in the hippocampus. Mediates Zn(2+) reuptake from the secreted milk within the alveolar lumen. |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q99K24}; Multi-pass membrane protein. Apical cell membrane {ECO:0000250|UniProtKB:Q99K24}; Multi-pass membrane protein. Note=Localized primarily at the cell surface but also found in a perinuclear compartment in HC11 cells. In mammary epithelial cell, localized primary to the apical membrane {ECO:0000250|UniProtKB:Q99K24} |

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Provided below are standard protocols that you may find useful for product applications.
References
Ollila,H.M., et.al., Mol. Psychiatry 14 (4), 351-353 (2009)
Kahmann,L., et.al, Rejuvenation Res 11 (1), 227-237 (2008)

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