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FOXL1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q12952 |
| Other Accession | Q64731 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 36490 Da |
| Antigen Region | 94-119 aa |
| Gene ID | 2300 |
|---|---|
| Other Names | Forkhead box protein L1, Forkhead-related protein FKHL11, Forkhead-related transcription factor 7, FREAC-7, FOXL1, FKHL11, FREAC7 |
| Target/Specificity | This FOXL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-119 amino acids from the Central region of human FOXL1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FOXL1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FOXL1 |
|---|---|
| Synonyms | FKHL11, FREAC7 |
| Function | Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 and GLI3 transcription factors (By similarity). |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The forkhead domain is a 100-amino acid monomeric DNA binding motif originally identified as a region of homology between the Drosophila forkhead protein and rat HNF3. Pierrou et al. (1994) identified 7 human genes containing forkhead domains and designated them forkhead related activators (FREAC) 1 through 7.
References
Rivadeneira,F., et.al., Nat. Genet. 41 (11), 1199-1206 (2009)
Ferrell,R.E., et.al., Lymphat Res Biol 6 (2), 69-76 (2008)
Hassel,S., et.al., Proteomics 4 (5), 1346-1358 (2004)
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