TC10 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, ICC |
---|---|
Primary Accession | P17081 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | ARHQ; RASL7A; Rho related GTP binding protein RhoQ; Rhoq; TC10A; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 22659 Da |
Dilution | WB 1:500~1:2000 ICC/IF 1:50~1:200 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human TC10 |
Description | Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | RHOQ |
---|---|
Synonyms | ARHQ, RASL7A, TC10 |
Function | Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia. |
Cellular Location | Cytoplasm. Cell membrane; Lipid-anchor |

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