UBE4A Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC, ICC |
---|---|
Primary Accession | Q14139 |
Clonality | Monoclonal |
Other Names | UBE4A; UBOX2; UFD2; UFD2b; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 122561 Da |
Dilution | WB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:50 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human UBE4A |
Description | Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | UBE4A (HGNC:12499) |
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Function | Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:E9Q735}. |

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