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MTAP Antibody

Rabbit mAb

     
  •  - MTAP Antibody AP92902
    Western blot analysis of MTAP expression in (1) 293T cell lysate; (2) NIH/3T3 cell lysate.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, FC, ICC, IP
Primary Accession Q13126
Reactivity Rat
Clonality Monoclonal
Other Names BDMF; DMSFH; DMSMFH; LGMBF; MeSAdo phosphorylase; MSAP; MTAP; MTAPase;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 31236 Da
Additional Information
Dilution WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human MTAP
Description Plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name MTAP {ECO:0000255|HAMAP-Rule:MF_03155}
Synonyms MSAP
Function Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
Cellular Location Cytoplasm. Nucleus {ECO:0000255|HAMAP- Rule:MF_03155}
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)
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$ 350.00
$ 175.00
Cat# AP92902
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Availability: 4 weeks
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