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SH3BGRL3 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SH3BGRL3 Antibody (Center) AP9302c
    Western blot analysis of SH3BGRL3 Antibody (Center) (Cat. #AP9302c) in Neuro2a cell line lysates (35ug/lane). SH3BGRL3 (arrow) was detected using the purified Pab.
    detail
  • IHC-P - SH3BGRL3 Antibody (Center) AP9302c
    Formalin-fixed and paraffin-embedded human brain tissue reacted with SH3BGRL3 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q9H299
Other Accession Q3ZCL8
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 10438 Da
Antigen Region 24-52 aa
Additional Information
Gene ID 83442
Other Names SH3 domain-binding glutamic acid-rich-like protein 3, SH3 domain-binding protein 1, SH3BP-1, SH3BGRL3
Target/Specificity This SH3BGRL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the Central region of human SH3BGRL3.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSH3BGRL3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SH3BGRL3
Function Could act as a modulator of glutaredoxin biological activity (Probable). May play a role in cytoskeleton organization (PubMed:34380438).
Cellular Location Cytoplasm, cytosol. Cell projection, ruffle membrane. Nucleus
Tissue Location Ubiquitous (PubMed:11444877, PubMed:11404387). Expressed in heart, kidney and liver (at protein level) (PubMed:11404387). Expressed in brain, lung, spleen and skeletal muscle (PubMed:11404387).
Research Areas
Citations (0)
citation

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Background

SH3BGRL3 could act as a modulator of glutaredoxin biological activity.

References

Mazzocco,M., et.al., Biochem. Biophys. Res. Commun. 285 (2), 540-545 (2001)
Henn,A.D., et.al., FASEB J. 15 (7), 1315-1317 (2001)
Seo,J., et.al., Mol. Cells 10 (6), 733-739 (2000)

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$ 365.00
$ 140.00
Cat# AP9302c
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