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DcR1 / CD263 Antibody
Rabbit mAb
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- BACKGROUND
Application 
| WB, ICC |
|---|---|
| Primary Accession | O14798 |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Other Names | CD263; DCR1; Decoy Receptor 1; LIT; TRAILR3; TRID; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 27407 Da |
| Dilution | WB 1:500~1:2000 ICC/IF 1:50~1:200 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human DcR1 / CD263 |
| Description | DcR1/TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | TNFRSF10C |
|---|---|
| Synonyms | DCR1, LIT, TRAILR3, TRID |
| Function | Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL- R1 and R2 for binding to the ligand. |
| Cellular Location | Cell membrane; Lipid-anchor, GPI-anchor. |
| Tissue Location | Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart |
Research Areas
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Application Protocols
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$ 195.00
$ 385.00
Cat# AP93132
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